2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1) (AA 236-336) antibody

Details for Product No. ABIN395953
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Antigen
Synonyms fe38b07, wu:fe38b07, zgc:92356, DECR, NADPH, SDR18C1, 1200012F07Rik, Decr, Nadph
Epitope
AA 236-336
(7), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(28), (12), (12), (12), (12), (12), (12)
Host
Mouse
(17), (10), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(19), (10), (10), (8), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN395953
450.00 $
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Immunogen DECR1 (NP_001350, 236 a.a. ~ 336 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D4
Isotype IgG2a kappa
Specificity DECR1 (NP_001350, 236 a.a. ~ 336 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DECR1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 36068 DA
Gene ID 12406
NCBI Accession NP_001350
Research Area Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1) (AA 236-336) antibody DECR1 monoclonal antibody (M01), clone 3D4. Western Blot analysis of DECR1 expression in HepG2.
Background publications Pridgeon, Webber, Sha et al.: "Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes." in: The FEBS journal, Vol. 276, Issue 1, pp. 118-31, 2008 (PubMed).

Persson, Kallberg, Bray et al.: "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative." in: Chemico-biological interactions, Vol. 178, Issue 1-3, pp. 94-8, 2009 (PubMed).

Moe, Woon, De Silva et al.: "Association of acute ischemic stroke with the MTHFR C677T polymorphism but not with NOS3 gene polymorphisms in a Singapore population." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 15, Issue 12, pp. 1309-14, 2008 (PubMed).

Hosgood, Zhang, Shen et al.: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, 2009 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

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