Annexin A2 (ANXA2) (AA 1-339) antibody

Details for Product No. ABIN395987
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Antigen
Synonyms MGC53008, p36, anx2, lip2, lpc2, cal1h, lpc2d, pap-i, anx2l4, MGC76145, ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV, AW215814, Cal1h
Epitope
AA 1-339
(18), (8), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(109), (52), (47), (18), (14), (13), (4), (1), (1)
Host
Mouse
(94), (10), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (6), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(99), (60), (34), (23), (11), (10), (7), (6), (5), (3), (2), (2), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN395987
450.00 $
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Immunogen ANXA2 (AAH09564, 1 a.a. ~ 339 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3E8-B6
Isotype IgG1 kappa
Specificity ANXA2 (AAH09564, 1 a.a. ~ 339 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ANXA2
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 38604 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Annexin A2 (ANXA2) (AA 1-339) antibody Immunofluorescence of monoclonal antibody to ANXA2 on HeLa cell.[antibody concentration 10 µg/mL] Western blot analysis of ANXA2 over-expressed 293 cell line, cotransfected with ANXA2 Validated Chimera RNAi used as specificity and loading control.
anti-Annexin A2 (ANXA2) (AA 1-339) antibody (2) anti-Annexin A2 (ANXA2) (AA 1-339) antibody (Image 2)
Background publications Backes, Quinkert, Reiss et al.: "Role of annexin A2 in the production of infectious hepatitis C virus particles." in: Journal of virology, Vol. 84, Issue 11, pp. 5775-89, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Lisitskaia, Krakhmaleva, Shishkin: "[A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer]." in: Molekuliarnaia genetika, mikrobiologiia i virusologiia, Issue 2, pp. 34-7, 2010 (PubMed).

Li, Ke, Zhang et al.: "A role for the annexin A2 amino-terminal peptide in the plasmin-induced activation of human peripheral monocytes." in: Molecular immunology, Vol. 47, Issue 14, pp. 2405-10, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Validation Images
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