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Details for Product No. ABIN396082

Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) antibody

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Synonyms ACS1, LACS, FACL1, FACL2, LACS1, LACS2, Acas, Acas1, Acs, FACS, Facl2, ACS, COAA, zgc:110081
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396082
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
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Immunogen ACSL1 (NP_001986, 48 a.a. ~ 146 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G4
Isotype IgG2a kappa
Specificity ACSL1 (NP_001986, 48 a.a. ~ 146 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACSL1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 77943 DA
Gene ID 12406
UniProt NP_001986
Research Area Metabolism, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Kahn, Alquier, Carling et al.: "AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism." in: Cell metabolism, Vol. 1, Issue 1, pp. 15-25, 2005 (PubMed).

Soupene, Kuypers: "Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains." in: BMC molecular biology, Vol. 7, pp. 21, 2006 (PubMed).

Lu, Dollé, Imholz et al.: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, 2008 (PubMed).

Phillips, Goumidi, Bertrais et al.: "Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1793-800, 2010 (PubMed).

Alternatives for antigen "Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1)", type "Antibodies"
Hosts (43), (2)
Reactivities (42), (33), (33), (15), (15), (15), (12), (9), (1), (1)
Applications (36), (13), (10), (6), (4), (3)
Conjugates (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (6), (4), (2), (2), (1), (1)