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Secretory Carrier Membrane Protein 3 (SCAMP3) (AA 70-170) antibody

Details for Product No. ABIN396090
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Antigen
Synonyms scamp3, MGC84585, SCAMP3, MGC97532, C1orf3, Sc3, TU52, F11P17.4, F11P17_4, secretory carrier 3
Epitope
AA 70-170
(3), (3), (2), (2), (1)
Reactivity
Human
(21), (2), (1)
Host
Mouse
(16), (4), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2)
Application
ELISA, Western Blotting (WB)
(22), (12), (10), (2), (2), (2)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN396090
450.00 $
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Immunogen SCAMP3 (NP_005689, 70 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G4
Isotype IgG1 lambda
Specificity SCAMP3 (NP_005689, 70 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SCAMP3
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 38287 DA
Gene ID 12406
UniProt NP_005689
Research Area Cell Structure, Cell Cycle
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. Two transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Secretory Carrier Membrane Protein 3 (SCAMP3) (AA 70-170) antibody Detection limit for recombinant GST tagged SCAMP3 is approximately 0.3 ng/mL as a capture antibody.
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Aoh, Castle, Hubbard et al.: "SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling." in: Molecular biology of the cell, Vol. 20, Issue 6, pp. 1816-32, 2009 (PubMed).

Mota, Ramsden, Liu et al.: "SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking." in: Cellular microbiology, Vol. 11, Issue 8, pp. 1236-53, 2009 (PubMed).

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