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Details for Product No. ABIN396090

Secretory Carrier Membrane Protein 3 (SCAMP3) antibody

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Antigen
Synonyms C1orf3, Sc3, TU52, F11P17.4, F11P17_4, secretory carrier 3, scamp3, MGC84585, SCAMP3, MGC97532
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396090
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen SCAMP3 (NP_005689, 70 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G4
Isotype IgG1 lambda
Specificity SCAMP3 (NP_005689, 70 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SCAMP3
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 38287 DA
Gene ID 12406
UniProt NP_005689
Research Area Cell Structure, Cell Cycle
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. Two transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Aoh, Castle, Hubbard et al.: "SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling." in: Molecular biology of the cell, Vol. 20, Issue 6, pp. 1816-32, 2009 (PubMed).

Mota, Ramsden, Liu et al.: "SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking." in: Cellular microbiology, Vol. 11, Issue 8, pp. 1236-53, 2009 (PubMed).

Alternatives for antigen "Secretory Carrier Membrane Protein 3 (SCAMP3)", type "Antibodies"
Hosts (12), (4), (1)
Reactivities (16), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (17), (8), (5), (2), (1)
Conjugates (1), (1), (1)
Epitopes (3), (3), (1), (1)
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