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Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 81-179) antibody

Details for Product No. ABIN396109, Supplier: Log in to see
Antigen
  • tbl1xr1
  • zgc:63617
  • c21
  • dc42
  • ira1
  • TBLR1
  • TBL1XR1
  • wu:fc46g07
  • zgc:110312
  • C21
  • DC42
  • IRA1
  • RGD1560053
  • 8030499H02Rik
  • A630076E03Rik
  • AW539987
  • C230089I12Rik
  • Ira1
Epitope
AA 81-179
18
16
13
4
4
3
3
3
2
2
1
1
1
Reactivity
Human
68
19
18
2
1
1
1
1
1
Host
Mouse
53
16
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
56
24
14
12
11
10
9
2
1
1
1
1
1
Supplier
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Immunogen TBL1XR1 (-, 81 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G7
Isotype IgG1 kappa
Specificity TBL1XR1 (-, 81 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TBL1XR1 (TBL1XR1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 55595 DA
Gene ID 12406
NCBI Accession NP_078941
Research Area Cell Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 81-179) antibody (ABIN396109) Immunofluorescence of monoclonal antibody to TBL1XR1 on HeLa cell (antibody concentra...
Immunohistochemistry (IHC) image for anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 81-179) antibody (ABIN396109) anti-Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) (AA 81-179) antibody (Image 2)
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Rothenberg, Spergel, Sherrill et al.: "Common variants at 5q22 associate with pediatric eosinophilic esophagitis." in: Nature genetics, Vol. 42, Issue 4, pp. 289-91, 2010 (PubMed).

Parker, An, Barber et al.: "The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1." in: Genes, chromosomes & cancer, Vol. 47, Issue 12, pp. 1118-25, 2008 (PubMed).

Perissi, Scafoglio, Zhang et al.: "TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints." in: Molecular cell, Vol. 29, Issue 6, pp. 755-66, 2008 (PubMed).

Ishii, Kurasawa, Wong et al.: "Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 11, pp. 4179-84, 2008 (PubMed).