Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN396109

Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms C21, DC42, IRA1, TBLR1, RGD1560053, 8030499H02Rik, A630076E03Rik, AW539987, C230089I12Rik, Ira1, tbl1xr1, zgc:63617, c21, dc42, ira1, TBL1XR1, wu:fc46g07, zgc:110312
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396109
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen TBL1XR1 (-, 81 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G7
Isotype IgG1 kappa
Specificity TBL1XR1 (-, 81 a.a. ~ 179 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TBL1XR1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 55595 DA
Gene ID 12406
UniProt NP_078941
Research Area Cell Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence
Comment

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Ishii, Kurasawa, Wong et al.: "Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 11, pp. 4179-84, 2008 (PubMed).

Perissi, Scafoglio, Zhang et al.: "TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints." in: Molecular cell, Vol. 29, Issue 6, pp. 755-66, 2008 (PubMed).

Parker, An, Barber et al.: "The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1." in: Genes, chromosomes & cancer, Vol. 47, Issue 12, pp. 1118-25, 2008 (PubMed).

Rothenberg, Spergel, Sherrill et al.: "Common variants at 5q22 associate with pediatric eosinophilic esophagitis." in: Nature genetics, Vol. 42, Issue 4, pp. 289-91, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Alternatives for antigen "Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1)", type "Antibodies"
Hosts (32), (9)
Reactivities (41), (19), (18), (14), (14), (14), (13), (1), (1), (1), (1)
Applications (32), (11), (10), (7), (4), (4), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (3), (2), (2), (2), (1), (1), (1)
Beacon