|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Decorin (DCN) antibody
|Synonyms||CSCD, PG40, PGII, PGS2, DSPG2, SLRR1B, MGC94682, DCN, MGC127810|
Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||DCN (AAH05322, 1 a.a. ~ 360 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: DSPG2, PG40, PGII, PGS2, SLRR1B decorin|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||DCN (AAH05322, 1 a.a. ~ 360 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||39747 DA|
Background: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cancer, Cell Structure|
|Restrictions||For Research Use only|
Dimasi, Burdon, Hewitt et al.: "Candidate gene study to investigate the genetic determinants of normal variation in central corneal thickness." in: Molecular vision, Vol. 16, pp. 562-9, 2010 (PubMed).
Mohan, Gupta, Mehan et al.: "Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblasts." in: Experimental eye research, Vol. 91, Issue 2, pp. 238-45, 2010 (PubMed).
Swan, Murthi, Rajaraman et al.: "Decorin expression is decreased in human idiopathic fetal growth restriction." in: Reproduction, fertility, and development, Vol. 22, Issue 6, pp. 949-55, 2010 (PubMed).
Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).
Johnatty, Beesley, Chen et al.: "Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"." in: PLoS genetics, Vol. 6, Issue 7, pp. e1001016, 2010 (PubMed).