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ICAM-1 antibody (Intercellular Adhesion Molecule 1) (AA 1-533)

Details for Product anti-ICAM1 Antibody No. ABIN396158, Supplier: Log in to see
Antigen
  • BB2
  • CD54
  • P3.58
  • Icam-1
  • Ly-47
  • MALA-2
  • ICAM
  • ICAM-1
  • ICAM1
  • intercellular adhesion molecule 1
  • intercellular adhesion molecule-1
  • intercellular adhesion molecule-1 precursor
  • ICAM1
  • Icam1
  • ICAM-1
Alternatives
anti-Human ICAM-1 antibody for Flow Cytometry
Epitope
AA 1-533
40
17
15
15
12
11
11
11
10
8
7
7
6
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
727
172
155
28
13
9
3
1
1
1
1
Host
Mouse
565
261
83
8
8
7
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This ICAM-1 antibody is un-conjugated
80
77
76
21
20
19
14
13
11
11
10
9
9
9
9
9
6
6
6
6
5
5
4
4
4
4
4
4
4
3
3
2
2
1
Application
ELISA, Western Blotting (WB)
558
401
267
199
177
151
142
74
53
53
34
18
14
14
12
10
9
8
7
6
6
6
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
Options
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Immunogen ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3H8-2G6
Isotype IgG1 kappa
Specificity ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ICAM1 (ICAM1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 57825 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-ICAM-1 antibody (Intercellular Adhesion Molecule 1) (AA 1-533) (ABIN396158) Detection limit for recombinant GST tagged ICAM1 is approximately 0.1 ng/mL as a capt...
Background publications Cserti-Gazdewich, Dzik, Erdman, Ssewanyana, Dhabangi, Musoke, Kain: "Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda." in: Malaria journal, Vol. 9, pp. 233, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Beckers, Ruven, Haas, Doevendans, ten Cate, Prins, Biesma: "Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism." in: European journal of internal medicine, Vol. 21, Issue 4, pp. 289-92, 2010 (PubMed).

Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

van Buul, van Rijssel, van Alphen, Hoogenboezem, Tol, Hoeben, van Marle, Mul, Hordijk: "Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium." in: PLoS ONE, Vol. 5, Issue 6, pp. e11336, 2010 (PubMed).