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ICAM-1 antibody (Intercellular Adhesion Molecule 1) (AA 1-533)

Details for Product anti-ICAM1 Antibody No. ABIN396158, Supplier: Log in to see
Antigen
  • BB2
  • CD54
  • P3.58
  • Icam-1
  • Ly-47
  • MALA-2
  • ICAM
  • ICAM-1
  • ICAM1
Epitope
AA 1-533
38
18
13
13
10
8
8
7
6
6
5
5
5
5
5
5
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
580
145
108
11
10
7
1
1
1
Host
Mouse
418
253
77
10
8
5
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This ICAM-1 antibody is un-conjugated
77
77
68
20
10
10
8
8
6
4
4
4
4
4
4
3
2
2
1
1
1
Application
ELISA, Western Blotting (WB)
382
297
186
159
148
96
95
50
49
34
31
12
12
10
9
9
6
6
5
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Supplier
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Immunogen ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3H8-2G6
Isotype IgG1 kappa
Specificity ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ICAM1 (ICAM1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 57825 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-ICAM-1 antibody (Intercellular Adhesion Molecule 1) (AA 1-533) (ABIN396158) Detection limit for recombinant GST tagged ICAM1 is approximately 0.1 ng/mL as a capt...
Background publications Cserti-Gazdewich, Dzik, Erdman et al.: "Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda." in: Malaria journal, Vol. 9, pp. 233, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Beckers, Ruven, Haas et al.: "Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism." in: European journal of internal medicine, Vol. 21, Issue 4, pp. 289-92, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

van Buul, van Rijssel, van Alphen et al.: "Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium." in: PLoS ONE, Vol. 5, Issue 6, pp. e11336, 2010 (PubMed).