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Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-533) antibody

Details for Product No. ABIN396158
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Antigen
Synonyms BB2, CD54, P3.58, Icam-1, Ly-47, MALA-2, ICAM, ICAM-1, ICAM1
Epitope
AA 1-533
(34), (12), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(487), (130), (87), (41), (33), (18), (17), (1)
Host
Mouse
(291), (233), (54), (6), (5), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(56), (48), (32), (11), (10), (10), (9), (8), (8), (8), (8), (8), (8), (6), (4), (4), (4), (4), (2), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(310), (223), (122), (105), (102), (101), (95), (60), (41), (32), (32), (16), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN396158
450.00 $
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Immunogen ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3H8-2G6
Isotype IgG1 kappa
Specificity ICAM1 (AAH15969, 1 a.a. ~ 533 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ICAM1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 57825 DA
Gene ID 12406
Research Area Cell Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-533) antibody Detection limit for recombinant GST tagged ICAM1 is approximately 0.1 ng/mL as a capture antibody.
Background publications van Buul, van Rijssel, van Alphen et al.: "Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium." in: PLoS ONE, Vol. 5, Issue 6, pp. e11336, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Beckers, Ruven, Haas et al.: "Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism." in: European journal of internal medicine, Vol. 21, Issue 4, pp. 289-92, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Cserti-Gazdewich, Dzik, Erdman et al.: "Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda." in: Malaria journal, Vol. 9, pp. 233, 2010 (PubMed).

Validation Images
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