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Galactose-1-Phosphate Uridylyltransferase (GALT) (AA 1-380) antibody

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Synonyms CG9232, Dmel\\CG9232, GALT, dGALT, AW553376, AW108479, Gal, Ggta, Ggta-1, alpha3GalT
AA 1-380
(22), (10), (5), (2), (2), (1), (1)
(68), (16), (15), (1), (1), (1), (1), (1)
(58), (12)
Clonality (Clone)
Monoclonal ()
(5), (5), (5), (2), (2), (2), (1)
Western Blotting (WB)
(60), (39), (13), (9), (4), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen GALT (AAH15045, 1 a.a. ~ 380 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4C11
Isotype IgG2a kappa
Specificity GALT (AAH15045, 1 a.a. ~ 380 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name GALT (GALT Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 43363 DA
Gene ID 12406
Research Area Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000

Background: Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Galactose-1-Phosphate Uridylyltransferase (GALT) (AA 1-380) antibody (ABIN396266) Western Blot analysis of GALT expression in transfected 293T cell line by GALT monocl...
Immunohistochemistry (IHC) image for anti-Galactose-1-Phosphate Uridylyltransferase (GALT) (AA 1-380) antibody (ABIN396266) anti-Galactose-1-Phosphate Uridylyltransferase (GALT) (AA 1-380) antibody (Image 2)
Background publications Ko, Chang, Song et al.: "Molecular and biochemical characterization of the GALT gene in Korean patients with galactose-1-phosphate uridyltransferase deficiency." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 411, Issue 19-20, pp. 1506-10, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Ounap, Joost, Temberg et al.: "Classical galactosemia in Estonia: selective neonatal screening, incidence, and genotype/phenotype data of diagnosed patients." in: Journal of inherited metabolic disease, Vol. 33, Issue 2, pp. 175-6, 2010 (PubMed).

Facchiano, Marabotti: "Analysis of galactosemia-linked mutations of GALT enzyme using a computational biology approach." in: Protein engineering, design & selection : PEDS, Vol. 23, Issue 2, pp. 103-13, 2010 (PubMed).

Nijland, Hartog, Wevers et al.: "Galactose-1-phosphate uridyl transferase deficiency is not associated with Müllerian aplasia in Dutch patients." in: Journal of pediatric and adolescent gynecology, Vol. 22, Issue 4, pp. 229-31, 2009 (PubMed).

Catalog No. ABIN396266
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