Inducible T-Cell Co-Stimulator Ligand (ICOSLG) antibody

Antigen: Inducible T-Cell Co-Stimulator Ligand (ICOSLG)

Synonyms: B7H2, GL50, B7-H2, B7RP1, CD275, ICOSL, LICOS, B7RP-1, ICOS-L, KIAA0653, B7h, GI50, GL50-B, Icoslg, Ly115l, AU044799, BG071784, mKIAA0653, ICOSLG, Icosl, RGD1562791

Clonality: Monoclonal (4D12)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396321

Additional Information

Alternative name: ICOSLG

Gene ID: 23308

Immunogen: ICOSLG (AAH64637, 20 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 4D12

Description: Other names: B7H2, B7H2, B7RP1, B7RP1, CD275, GL50, ICOSL, ICOSL, KIAA0653, LICOS inducible T-cell co-stimulator ligand

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: ICOSLG (AAH64637, 20 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 33349 DA

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged ICOSLG is approximately 0.1ng/ml as a capture antibody.

Publications

Product: Wang, Baldassano, Zhang et al.: "Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects." in: Human molecular genetics, Vol. 19, Issue 10, pp. 2059-67, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Pan, Yang, Chen et al.: "Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function." in: Immunogenetics, Vol. 62, Issue 4, pp. 237-51, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).