S100 Calcium Binding Protein A10 (S100A10) antibody

Antigen: S100 Calcium Binding Protein A10 (S100A10)

Synonyms: 42C, P11, p10, GP11, ANX2L, CAL1L, CLP11, Ca[1], ANX2LG, MGC111133, p11, CAL12, Cal1l, AA409961, AL024248, S100A10, s100a10

Clonality: Monoclonal (4D2-F1)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396326

Additional Information

Alternative name: S100A10

Gene ID: 6281

Immunogen: S100A10 (AAH15973, 1 a.a. ~ 98 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 4D2-F1

Description: Other names: 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10 S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: S100A10 (AAH15973, 1 a.a. ~ 98 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 11203 DA

Comments:

Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged S100A10 is approximately 0.1ng/ml as a capture antibody.

Publications

Product: Petersson, Shubbar, Enerbäck et al.: "Expression patterns of S100 proteins in melanocytes and melanocytic lesions." in: Melanoma research, Vol. 19, Issue 4, pp. 215-25, 2009 (PubMed).

Stemmler, Nothnagel, Parwez et al.: "Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients." in: International journal of immunogenetics, Vol. 36, Issue 4, pp. 217-22, 2009 (PubMed).

Landa, Ruiz-Llorente, Montero-Conde et al.: "The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors." in: PLoS genetics, Vol. 5, Issue 9, pp. e1000637, 2009 (PubMed).

Muimo: "Regulation of CFTR function by annexin A2-S100A10 complex in health and disease." in: General physiology and biophysics, Vol. 28 Spec No Focus, pp. F14-9, 2010 (PubMed).

Jung, Murzik, Wehder et al.: "Regulation of cellular actin architecture by S100A10." in: Experimental cell research, Vol. 316, Issue 7, pp. 1234-40, 2010 (PubMed).