Septin 3 (SEPT3) (AA 236-346) antibody

Details for Product No. ABIN396346
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Antigen
Synonyms SEPT3, sept3, MGC69255, GEF, GEF-H1, GEFH1, LFP40, P40, SEP3, bK250D10.3, 3110018K01Rik, AV154067, B530002E20Rik, Sep3, Sep-03, zgc:110051, 4930471M23Rik, 5730478O19Rik, ANT2BP, Tango9
Epitope
AA 236-346
(8), (7), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(42), (24), (24), (15), (13), (13), (11)
Host
Mouse
(27), (10), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(32), (21), (9), (5)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN396346
450.00 $
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Immunogen SEPT3 (NP_663786, 236 a.a. ~ 346 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4D8
Isotype IgG1 kappa
Specificity SEPT3 (NP_663786, 236 a.a. ~ 346 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name Sep 03
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 40704 DA
Gene ID 12406
NCBI Accession NP_663786
Research Area Cancer, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Septin 3 (SEPT3) (AA 236-346) antibody SEPT3 monoclonal antibody (M03), clone 4D8 Western Blot analysis of 3-Sep expression in Jurkat. Detection limit for recombinant GST tagged 3-Sep is approximately 0.1 ng/mL as a capture antibody.
anti-Septin 3 (SEPT3) (AA 236-346) antibody (2) anti-Septin 3 (SEPT3) (AA 236-346) antibody (Image 2)
Background publications Xue, Tsang, Gai et al.: "Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals." in: Journal of neurochemistry, Vol. 91, Issue 3, pp. 579-90, 2004 (PubMed).

Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Validation Images
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