Septin 3 (SEPT3) antibody

Antigen: Septin 3 (SEPT3)

Synonyms: SEP3, MGC133218, bK250D10.3, Sep3, AV154067, 3110018K01Rik, B530002E20Rik, anon-EST:Liang-2.18, CG8705, clone 2.18, DmelCG8705, E(sina)44C, E(sina)8, l(2)02502, Pnut, PNUT, SEPT3, zgc:110051, sept3, MGC69255, MGC143057

Clonality: Monoclonal (4D8)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396346

Additional Information

Alternative name: Sep 03

Gene ID: 55964

UniProt: NP_663786

Immunogen: SEPT3 (NP_663786, 236 a.a. ~ 346 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 4D8

Description: Other names: SEP3, bK250D10.3 septin 3

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: SEPT3 (NP_663786, 236 a.a. ~ 346 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 40704 DA

Comments:

Background: This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Synonyms: SEP3, MGC133218, bK250D10.3, Sep3, AV154067, 3110018K01Rik, B530002E20Rik, anon-EST:Liang-2.18, CG8705, clone 2.18, DmelCG8705, E(sina)44C, E(sina)8, l(2)02502, Pnut, PNUT, SEPT3, zgc:110051, sept3, MGC69255, MGC143057

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cancer, Cell Structure

Restrictions: For Research Use only

Images

SEPT3 monoclonal antibody (M03), clone 4D8 Western Blot analysis of 3-Sep expression in Jurkat ( Cat # L017V1 ). Detection limit for recombinant GST tagged 3-Sep is approximately 0.1ng/ml as a capture antibody.

anti-Septin 3 (SEPT3) antibody (Image 2)

Publications

Product: Xue, Tsang, Gai et al.: "Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals." in: Journal of neurochemistry, Vol. 91, Issue 3, pp. 579-90, 2004 (PubMed).

Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).