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LIM and SH3 Protein 1 (LASP1) (AA 1-262) antibody

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Synonyms lasp1, MGC53336, LASP1, MGC89667, Lasp-1, MLN50, AA408629, Def-4, SH3P6, Tg(Col1a1-lacZ)1Ngma, fb92f05, wu:fb92f05, zgc:77542, lasp-1, mln50
AA 1-262
(33), (24), (17), (13), (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(98), (21), (20), (10), (6), (5), (4), (4), (2), (2), (1)
(53), (42), (3)
Clonality (Clone)
Monoclonal ()
(4), (4), (4), (4), (4), (4)
Western Blotting (WB)
(92), (52), (12), (6), (5), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen LASP1 (AAH12460, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F5
Isotype IgG2a kappa
Specificity LASP1 (AAH12460, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name LASP1 (LASP1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 29717 DA
Gene ID 12406
Research Area Cell Structure
Application Notes Western blot = 1:500-1000

Background: This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-LIM and SH3 Protein 1 (LASP1) (AA 1-262) antibody (ABIN396389) Western Blot analysis of LASP1 expression in transfected 293T cell line by LASP1 mono...
Background publications Frietsch, Grunewald, Jasper et al.: "Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer." in: British journal of cancer, Vol. 102, Issue 11, pp. 1645-53, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Traenka, Hauck, Lewandrowski et al.: "Integrin-dependent translocation of LASP-1 to the cytoskeleton of activated platelets correlates with LASP-1 phosphorylation at tyrosine 171 by Src-kinase." in: Thrombosis and haemostasis, Vol. 102, Issue 3, pp. 520-8, 2009 (PubMed).

Salvi, Bongarzone, Miccichè et al.: "Proteomic identification of LASP-1 down-regulation after RNAi urokinase silencing in human hepatocellular carcinoma cells." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 2, pp. 207-19, 2009 (PubMed).

Wang, Feng, Xiao et al.: "LIM and SH3 protein 1 (Lasp1) is a novel p53 transcriptional target involved in hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 3, pp. 528-37, 2009 (PubMed).

Catalog No. ABIN396389
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