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Details for Product No. ABIN396389

LIM and SH3 Protein 1 (LASP1) antibody

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Antigen
Synonyms MLN50, Lasp-1, Def-4, SH3P6, AA408629, Tg(Col1a1-lacZ)1Ngma, fb92f05, zgc:77542, wu:fb92f05, LASP1, DKFZp459O1227, lasp1, MGC53336, MGC89667, mln50, lasp-1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396389
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen LASP1 (AAH12460, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F5
Isotype IgG2a kappa
Specificity LASP1 (AAH12460, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name LASP1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 29717 DA
Gene ID 12406
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Wang, Feng, Xiao et al.: "LIM and SH3 protein 1 (Lasp1) is a novel p53 transcriptional target involved in hepatocellular carcinoma." in: Journal of hepatology, Vol. 50, Issue 3, pp. 528-37, 2009 (PubMed).

Salvi, Bongarzone, Miccichè et al.: "Proteomic identification of LASP-1 down-regulation after RNAi urokinase silencing in human hepatocellular carcinoma cells." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 2, pp. 207-19, 2009 (PubMed).

Traenka, Hauck, Lewandrowski et al.: "Integrin-dependent translocation of LASP-1 to the cytoskeleton of activated platelets correlates with LASP-1 phosphorylation at tyrosine 171 by Src-kinase." in: Thrombosis and haemostasis, Vol. 102, Issue 3, pp. 520-8, 2009 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Frietsch, Grunewald, Jasper et al.: "Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer." in: British journal of cancer, Vol. 102, Issue 11, pp. 1645-53, 2010 (PubMed).

Alternatives for antigen "LIM and SH3 Protein 1 (LASP1)", type "Antibodies"
Hosts (16), (16), (3)
Reactivities (27), (8), (7), (7), (5), (2), (2), (2), (2), (1)
Applications (32), (17), (5), (1), (1), (1)
Epitopes (8), (6), (3), (2), (2), (2), (2), (1)
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