Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) antibody

Details for Product No. ABIN396397
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Antigen
Synonyms FABP, H-FABP, Mdgi, Fabph1, Fabph4, Fabph-1, Fabph-4, FABP-3
Reactivity
Human
(146), (37), (36), (17), (15), (14), (2), (1), (1)
Host
Mouse
(95), (66), (5), (3), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(18), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(118), (89), (45), (44), (24), (21), (16), (10), (7), (7), (6), (6), (6), (5), (5), (3), (2), (2), (2), (2), (2), (1)
Pubmed 5 references available
Catalog no. ABIN396397
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Immunogen FABP3 (AAH07021, 1 a.a. ~ 134 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F6-1D6
Isotype IgG2a kappa
Specificity FABP3 (AAH07021, 1 a.a. ~ 134 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name FABP3
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 14858 DA
Gene ID 12406
Research Area Cancer, Cell Cycle, Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) antibody Western blot analysis of FABP3 over-expressed 293 cell line, cotransfected with FABP3 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of FABP3 expression in transfected 293T cell line by FABP3 monoclonal antibody (M01), clone 4F6-1D6. Lane 1: FABP3 transfected lysate(14.9 KDa). Lane 2: Non-transfected lysate.
anti-Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) antibody (2) anti-Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) antibody (Image 2)
Background publications Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Boscheri, Wunderlich, Langer et al.: "Correlation of heart-type fatty acid-binding protein with mortality and echocardiographic data in patients with pulmonary embolism at intermediate risk." in: American heart journal, Vol. 160, Issue 2, pp. 294-300, 2010 (PubMed).

Jassim, Fernø, Theisen et al.: "Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia." in: Pharmacopsychiatry, Vol. 44, Issue 1, pp. 15-20, 2011 (PubMed).

Hosts (95), (66), (5), (3), (2), (1)
Reactivities (146), (37), (36), (17), (15), (14), (2), (1), (1)
Applications (118), (89), (45), (44), (24), (21), (16), (10), (7), (7), (6), (6), (6), (5), (5), (3), (2), (2), (2), (2), (2), (1)
Conjugates (18), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (12), (4), (3), (3), (2), (2), (1), (1)
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