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FABP3 antibody (Fatty Acid Binding Protein 3, Muscle and Heart) (AA 1-134)

Details for Product anti-FABP3 Antibody No. ABIN396397, Supplier: Log in to see
Antigen
  • FABP
  • FABP-3
  • fabp3
  • FABP11
  • Fabph-1
  • Fabph-4
  • Fabph1
  • Fabph4
  • H-FABP
  • M-FABP
  • MDGI
  • Mdgi
  • O-FABP
Epitope
AA 1-134
34
14
13
8
7
5
4
4
2
2
1
1
1
1
Reactivity
Human
327
52
49
6
5
2
1
1
Host
Mouse
172
159
12
7
1
Clonality (Clone)
Monoclonal ()
Conjugate
This FABP3 antibody is un-conjugated
46
29
22
10
10
10
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
208
200
68
37
30
22
16
11
11
10
7
7
7
5
5
2
2
2
1
1
1
1
1
Supplier
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Immunogen FABP3 (AAH07021, 1 a.a. ~ 134 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F6-1D6
Isotype IgG2a kappa
Specificity FABP3 (AAH07021, 1 a.a. ~ 134 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name FABP3 (FABP3 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 14858 DA
Gene ID 12406
Research Area Cancer, Cell Cycle, Metabolism, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-FABP3 antibody (Fatty Acid Binding Protein 3, Muscle and Heart) (AA 1-134) (ABIN396397) Western blot analysis of FABP3 over-expressed 293 cell line, cotransfected with FABP3...
Immunohistochemistry (IHC) image for anti-FABP3 antibody (Fatty Acid Binding Protein 3, Muscle and Heart) (AA 1-134) (ABIN396397) anti-Fatty Acid Binding Protein 3, Muscle and Heart (FABP3) (AA 1-134) antibody (Image 2)
Background publications Jassim, Fernø, Theisen, Haberhausen, Christoforou, Håvik, Gebhardt, Remschmidt, Mehler-Wex, Hebebrand, Lehellard, Steen: "Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia." in: Pharmacopsychiatry, Vol. 44, Issue 1, pp. 15-20, 2011

Boscheri, Wunderlich, Langer, Schoen, Wiedemann, Stolte, Elmer, Barthel, Strasser: "Correlation of heart-type fatty acid-binding protein with mortality and echocardiographic data in patients with pulmonary embolism at intermediate risk." in: American heart journal, Vol. 160, Issue 2, pp. 294-300, 2010

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010