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ACAA2 antibody (Acetyl-CoA Acyltransferase 2) (AA 151-261)

Details for Product anti-ACAA2 Antibody No. ABIN396558, Supplier: Log in to see
Antigen
  • 0610011L04Rik
  • AI255831
  • AI265397
  • D18Ertd240e
  • DSAEC
Epitope
AA 151-261
8
6
3
2
Reactivity
Human
49
22
19
7
6
2
2
2
2
Host
Mouse
30
22
Clonality (Clone)
Monoclonal ()
Conjugate
This ACAA2 antibody is un-conjugated
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
48
25
23
18
9
7
1
Supplier
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Immunogen ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5C4
Isotype IgG1 kappa
Specificity ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACAA2 (ACAA2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 41924 DA
Gene ID 12406
NCBI Accession NP_006102
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ACAA2 antibody (Acetyl-CoA Acyltransferase 2) (AA 151-261) (ABIN396558) Immunofluorescence of monoclonal antibody to ACAA2 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-ACAA2 antibody (Acetyl-CoA Acyltransferase 2) (AA 151-261) (ABIN396558) anti-Acetyl-CoA Acyltransferase 2 (ACAA2) (AA 151-261) antibody (Image 2)
Background publications Hu, Lui, Mak, Chu, Lee, Poon, Tsui, Ko, Baum, Tam, Li, Tomlinson: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).

Fontaine-Bisson, Renström, Rolandsson, , Payne, Hallmans, Barroso, Franks: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Cao, Liu, Tang, Bao, Shen, Yuan, Zhao, Lu: "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines." in: Biochimica et biophysica acta, Vol. 1780, Issue 6, pp. 873-80, 2008 (PubMed).

Kathiresan, Melander, Guiducci, Surti, Burtt, Rieder, Cooper, Roos, Voight, Havulinna, Wahlstrand, Hedner, Corella, Tai, Ordovas, Berglund, Vartiainen, Jousilahti, Hedblad, Taskinen, Newton-Cheh et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ..." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Willer, Sanna, Jackson, Scuteri, Bonnycastle, Clarke, Heath, Timpson, Najjar, Stringham, Strait, Duren, Maschio, Busonero, Mulas, Albai, Swift, Morken, Narisu, Bennett, Parish, Shen, Galan, Meneton, Hercberg, Zelenika, Chen, Li, Scott, Scheet, Sundvall, W: "Newly identified loci that influence lipid concentrations and risk of coronary artery disease." in: Nature genetics, Vol. 40, Issue 2, pp. 161-9, 2008 (PubMed).