Acetyl-CoA Acyltransferase 2 (ACAA2) antibody

Antigen: Acetyl-CoA Acyltransferase 2 (ACAA2)

Synonyms: ACAT2, ARGP2, ACACT2, MGC116732, DSAEC, FLJ35992, FLJ95265, fb10a06, fb53f08, wu:fb10a06, wu:fb53f08, Tcp-1x, AW742799, Tcp1-rs1, MGC36039, D15Wsu97e, Acat-2, Ab2-076, MGC95138, acat2, MGC76038, fb59b11, zgc:56036, wu:fb59b11, MGC140551, ACAA2, MGC127380, MGC89951, ACETOACETYL-COA THIOLASE 2, EMB1276, EMBRYO DEFECTIVE 1276, MIF21.12, MIF21_12, DKFZp469F1024, DKFZp470L0527

Clonality: Monoclonal (5C4)

Host: Mouse

Reactivity: Human

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396558

Additional Information

Alternative name: ACAA2

Gene ID: 10449

UniProt: NP_006102

Immunogen: ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 5C4

Description: Other names: DSAEC acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 41924 DA

Comments:

Background: The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

Synonyms: ACAT2, ARGP2, ACACT2, MGC116732, DSAEC, FLJ35992, FLJ95265, fb10a06, fb53f08, wu:fb10a06, wu:fb53f08, Tcp-1x, AW742799, Tcp1-rs1, MGC36039, D15Wsu97e, Acat-2, Ab2-076, MGC95138, acat2, MGC76038, fb59b11, zgc:56036, wu:fb59b11, MGC140551, ACAA2, MGC127380, MGC89951, ACETOACETYL-COA THIOLASE 2, EMB1276, EMBRYO DEFECTIVE 1276, MIF21.12, MIF21_12, DKFZp469F1024, DKFZp470L0527

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

Immunofluorescence of monoclonal antibody to ACAA2 (AT1016a) on HeLa cell . [antibody concentration 40 ug/ml] ACAA2 monoclonal antibody (M01), clone 5C4 Western Blot analysis of ACAA2 expression in HeLa ( Cat # L013V1 ).

anti-Acetyl-CoA Acyltransferase 2 (ACAA2) antibody (Image 2)

Publications

Product: Willer, Sanna, Jackson et al.: "Newly identified loci that influence lipid concentrations and risk of coronary artery disease." in: Nature genetics, Vol. 40, Issue 2, pp. 161-9, 2008 (PubMed).

Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Cao, Liu, Tang et al.: "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines." in: Biochimica et biophysica acta, Vol. 1780, Issue 6, pp. 873-80, 2008 (PubMed).

Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).