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Details for Product No. ABIN396558

Acetyl-CoA Acyltransferase 2 (ACAA2) antibody

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Antigen
Synonyms
DSAEC, 0610011L04Rik, AI255831, AI265397, D18Ertd240e, fb10a06, fb53f08, wu:fb10a06, wu:fb53f08, fb59b11, zgc:56036, wu:fb59b11, EMB1276, EMBRYO DEFECTIVE 1276, MIF21.12, MIF21_12, acetoacetyl-CoA thi ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396558
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5C4
Isotype IgG1 kappa
Specificity ACAA2 (NP_006102, 151 a.a. ~ 261 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ACAA2
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 41924 DA
Gene ID 12406
UniProt NP_006102
Research Area Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence
Comment

Background: The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Willer, Sanna, Jackson et al.: "Newly identified loci that influence lipid concentrations and risk of coronary artery disease." in: Nature genetics, Vol. 40, Issue 2, pp. 161-9, 2008 (PubMed).

Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Cao, Liu, Tang et al.: "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines." in: Biochimica et biophysica acta, Vol. 1780, Issue 6, pp. 873-80, 2008 (PubMed).

Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Hu, Lui, Mak et al.: "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 634-7, 2010 (PubMed).

Alternatives for antigen "Acetyl-CoA Acyltransferase 2 (ACAA2)", type "Antibodies"
Hosts (10), (9)
Reactivities (18), (8), (8), (2), (2), (2), (2)
Applications (19), (8), (8), (8), (2)
Epitopes (3), (2), (1), (1)
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