Hedgehog Interacting Protein (HHIP) (AA 21-121) antibody

Details for Product No. ABIN396574
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Antigen
Synonyms fd99f01, wu:fc52e12, wu:fd99f01, zgc:153478, Xhip, hip, HIP, Hhip1, RGD1564108
Epitope
AA 21-121
(8), (7), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(41), (17), (15), (12), (12), (12), (4)
Host
Mouse
(36), (9), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(35), (18), (11), (10), (6), (2), (2), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN396574
450.00 $
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Immunogen HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5D11
Isotype IgG2b kappa
Specificity HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name HHIP
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 78851 DA
Gene ID 12406
NCBI Accession NP_071920
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Hedgehog Interacting Protein (HHIP) (AA 21-121) antibody HHIP monoclonal antibody (M01), clone 5D11 Western Blot analysis of HHIP expression in Hela NE.
anti-Hedgehog Interacting Protein (HHIP) (AA 21-121) antibody (2) anti-Hedgehog Interacting Protein (HHIP) (AA 21-121) antibody (Image 2)
Background publications Cho, Boutaoui, Klanderman et al.: "Variants in FAM13A are associated with chronic obstructive pulmonary disease." in: Nature genetics, Vol. 42, Issue 3, pp. 200-2, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Liu, Medland, Wright et al.: "Genome-wide association study of height and body mass index in Australian twin families." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 2, pp. 179-93, 2010 (PubMed).

Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

Pillai, Kong, Edwards et al.: "Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 182, Issue 12, pp. 1498-505, 2010 (PubMed).

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