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HHIP antibody (Hedgehog Interacting Protein) (AA 21-121)

Details for Product anti-HHIP Antibody No. ABIN396574, Supplier: Login to see
Antigen
  • fd99f01
  • wu:fc52e12
  • wu:fd99f01
  • zgc:153478
  • Xhip
  • hip
  • HIP
  • Hhip1
  • RGD1564108
Alternatives
anti-Human HHIP antibody for Western Blotting
Epitope
AA 21-121
17
15
13
4
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
56
23
20
3
2
1
Host
Mouse
56
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This HHIP antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
45
23
11
9
8
2
2
1
1
1
1
Supplier
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Immunogen HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5D11
Isotype IgG2b kappa
Specificity HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name HHIP (HHIP Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 78851 DA
Gene ID 12406
NCBI Accession NP_071920
Research Area Cell Structure
Pathways Hedgehog Signaling
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-HHIP antibody (Hedgehog Interacting Protein) (AA 21-121) (ABIN396574) HHIP monoclonal antibody (M01), clone 5D11 Western Blot analysis of HHIP expression i...
Immunohistochemistry (IHC) image for anti-HHIP antibody (Hedgehog Interacting Protein) (AA 21-121) (ABIN396574) anti-Hedgehog Interacting Protein (HHIP) (AA 21-121) antibody (Image 2)
Background publications Pillai, Kong, Edwards et al.: "Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 182, Issue 12, pp. 1498-505, 2010 (PubMed).

Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

Liu, Medland, Wright et al.: "Genome-wide association study of height and body mass index in Australian twin families." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 2, pp. 179-93, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Cho, Boutaoui, Klanderman et al.: "Variants in FAM13A are associated with chronic obstructive pulmonary disease." in: Nature genetics, Vol. 42, Issue 3, pp. 200-2, 2010 (PubMed).