Hedgehog Interacting Protein (HHIP) antibody

Antigen: Hedgehog Interacting Protein (HHIP)

Synonyms: fd99f01, MGC153478, wu:fc52e12, wu:fd99f01, zgc:153478, HIP, FLJ20992, FLJ90230, hhip, MGC53432, hip, MGC89559, RGD1564108, HHIP, MGC157270, Hhip1

Clonality: Monoclonal (5D11)

Host: Mouse

Reactivity: Human

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396574

Additional Information

Alternative name: HHIP

Gene ID: 64399

UniProt: NP_071920

Immunogen: HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2b kappa

Clone: 5D11

Description: Other names: FLJ20992, FLJ90230, HIPhedgehog interacting protein

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: HHIP (NP_071920, 21 a.a. ~ 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 78851 DA

Comments:

Background: This gene encodes a protein similar to the mouse hedgehog-interacting protein, a regulatory component of the hedgehog signalling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml

Concentration: 0.5 mg/ml

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

HHIP monoclonal antibody (M01), clone 5D11 Western Blot analysis of HHIP expression in Hela NE ( Cat # L013V3 ). HHIP monoclonal antibody (M01), clone 5D11. Western Blot analysis of HHIP expression in MCF-7 ( Cat # L046V1 ).

anti-Hedgehog Interacting Protein (HHIP) antibody (Image 2)

Publications

Product: Cho, Boutaoui, Klanderman et al.: "Variants in FAM13A are associated with chronic obstructive pulmonary disease." in: Nature genetics, Vol. 42, Issue 3, pp. 200-2, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Liu, Medland, Wright et al.: "Genome-wide association study of height and body mass index in Australian twin families." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 2, pp. 179-93, 2010 (PubMed).

Zhao, Li, Bradfield et al.: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, 2010 (PubMed).

Pillai, Kong, Edwards et al.: "Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 182, Issue 12, pp. 1498-505, 2010 (PubMed).