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B-Cell CLL/lymphoma 7C (BCL7C) (AA 86-165) antibody

Details for Product No. ABIN396592, Supplier: Log in to see
Antigen
  • BCL7C
  • C230096E12Rik
Epitope
AA 86-165
16
15
4
2
2
1
1
1
Reactivity
Human
46
17
17
Host
Mouse
41
5
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
31
23
11
4
3
1
Supplier
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Immunogen BCL7C (NP_004756, 86 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5F1
Isotype IgG2a kappa
Specificity BCL7C (NP_004756, 86 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name BCL7C (BCL7C Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 23365 DA
Gene ID 12406
NCBI Accession NP_004756
Research Area Cancer, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-B-Cell CLL/lymphoma 7C (BCL7C) (AA 86-165) antibody (ABIN396592) Detection limit for recombinant GST tagged BCL7C is approximately 0.1 ng/mL as a capt...
Background publications Hosgood, Zhang, Shen et al.: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, 2009 (PubMed).

Liang, Caporaso, McMaster et al.: "Common genetic variants in candidate genes and risk of familial lymphoid malignancies." in: British journal of haematology, Vol. 146, Issue 4, pp. 418-23, 2009 (PubMed).

Morton, Purdue, Zheng et al.: "Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 4, pp. 1259-70, 2009 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).