B-Cell CLL/lymphoma 7C (BCL7C) antibody

Antigen: B-Cell CLL/lymphoma 7C (BCL7C)

Synonyms: C230096E12Rik, BCL7C

Clonality: Monoclonal (5F1)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396592

Additional Information

Alternative name: BCL7C

Gene ID: 9274

UniProt: NP_004756

Immunogen: BCL7C (NP_004756, 86 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 5F1

Description: Other names: B-cell CLL/lymphoma 7C

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: BCL7C (NP_004756, 86 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 23365 DA

Comments:

Background: This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cancer, Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged BCL7C is approximately 0.1ng/ml as a capture antibody.

Publications

Product: Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Morton, Purdue, Zheng et al.: "Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 4, pp. 1259-70, 2009 (PubMed).

Liang, Caporaso, McMaster et al.: "Common genetic variants in candidate genes and risk of familial lymphoid malignancies." in: British journal of haematology, Vol. 146, Issue 4, pp. 418-23, 2009 (PubMed).

Hosgood, Zhang, Shen et al.: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, 2009 (PubMed).