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Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1) (AA 28-97) antibody

Details for Product No. ABIN396604, Supplier: Log in to see
Antigen
  • An12g07570
  • lew
  • Syb-1
  • SYB1
  • syb1
  • Syb1
  • VAMP-1
  • vamp-1
  • VAMP1
Epitope
AA 28-97
9
3
2
2
2
2
2
2
1
1
1
Reactivity
Human
48
35
15
1
1
1
1
Host
Mouse
33
19
6
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
58
32
25
6
5
3
2
1
1
Supplier
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Immunogen VAMP1 (NP_055046, 28 a.a. ~ 97 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5F3
Isotype IgG2a lambda
Specificity VAMP1 (NP_055046, 28 a.a. ~ 97 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name VAMP1 (VAMP1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 12902 DA
Gene ID 12406
NCBI Accession NP_055046
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1) (AA 28-97) antibody (ABIN396604) VAMP1 monoclonal antibody (M01), clone 5F3. Western Blot analysis of VAMP1 expression...
Background publications Lu, Forsberg, Höög, Juhlin, Vukojević, Larsson, Conigrave, Delbridge, Gill, Bark, Farnebo, Bränström: "Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, Syntaxin1 and VAMP in human parathyroid tissue." in: Molecular and cellular endocrinology, Vol. 287, Issue 1-2, pp. 72-80, 2008

Kiel, Demissie, Dupuis, Lunetta, Murabito, Karasik: "Genome-wide association with bone mass and geometry in the Framingham Heart Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S14, 2007

Imabayashi, Mori, Gojo, Kiyono, Sugiyama, Irie, Isogai, Hata, Toyama, Umezawa: "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis." in: Experimental cell research, Vol. 288, Issue 1, pp. 35-50, 2003

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002

Pérez-Brangulí, Muhaisen, Blasi: "Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay." in: Molecular and cellular neurosciences, Vol. 20, Issue 2, pp. 169-80, 2002