|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Zinc Finger, BED-Type Containing 1 (ZBED1) antibody
|Synonyms||ALTE, DREF, TRAMP, hDREF, KIAA0785, ZBED1, ZBED1P|
Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||ZBED1 (NP_004720, 3 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: ALTE, KIAA0785, TRAMP zinc finger, BED-type containing 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||ZBED1 (NP_004720, 3 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||78156 DA|
Background: This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure|
|Restrictions||For Research Use only|
Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).
Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).
Yamashita, Komori, Higuchi et al.: "Human DNA replication-related element binding factor (hDREF) self-association via hATC domain is necessary for its nuclear accumulation and DNA binding." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7563-75, 2007 (PubMed).
Yamashita, Sano, Adachi et al.: "hDREF regulates cell proliferation and expression of ribosomal protein genes." in: Molecular and cellular biology, Vol. 27, Issue 6, pp. 2003-13, 2007 (PubMed).
Xin, Rual, Hirozane-Kishikawa et al.: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, 2009 (PubMed).
|Hosts||Rabbit (12), Mouse (4)|
|Reactivities||Human (17), Mouse (Murine) (3), Rat (Rattus) (1)|
|Applications||Western Blotting (WB) (16), ELISA (9), Immunohistochemistry (IHC) (4), Dot Blot (DB) (2), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1)|
|Conjugates||Biotin (1), FITC (1), HRP (1)|
|Epitopes||C-Term (2), Internal Region (1), Middle Region (1)|