|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) antibody
|Synonyms||ERIC1, MGC117382, MGC133242|
Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||TACC3 (NP_006333, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: ERIC1, MGC117382, MGC133242 transforming, acidic coiled-coil containing protein 3|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||TACC3 (NP_006333, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||90360 DA|
Background: The function of this gene has not yet been determined, however, it is speculated that it may be involved in cell growth and differentiation. Expression of this gene is up-regulated in some cancer cell lines, and in embryonic day 15 in mice.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cancer, Cell Structure|
|Restrictions||For Research Use only|
Jeng, Lin, Lin et al.: "Cdh1 controls the stability of TACC3." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 21, pp. 3529-36, 2009 (PubMed).
Couch, Wang, Bamlet et al.: "Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 251-7, 2010 (PubMed).
Kiemeney, Sulem, Besenbacher et al.: "A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer." in: Nature genetics, Vol. 42, Issue 5, pp. 415-9, 2010 (PubMed).
Olson, Wang, Pankratz et al.: "Centrosome-related genes, genetic variation, and risk of breast cancer." in: Breast cancer research and treatment, Vol. 125, Issue 1, pp. 221-8, 2010 (PubMed).
Lin, Hu, Shih: "Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability." in: The Journal of cell biology, Vol. 189, Issue 7, pp. 1097-105, 2010 (PubMed).
|Hosts||Mouse (11), Rabbit (9), Goat (1)|
|Reactivities||Human (20), Monkey (3), Mouse (Murine) (3), Rat (Rattus) (2)|
|Applications||Western Blotting (WB) (16), Immunofluorescence (IF) (12), Immunohistochemistry (IHC) (10), Flow Cytometry (FACS) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), ELISA (3), Immunocytochemistry (ICC) (2)|
|Epitopes||AA 689-838 (1), C-Term (1), Center (1), Internal Region (1)|