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Details for Product No. ABIN396697

Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) antibody

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Synonyms ERIC-1, ERIC1, Aint, C86661, Eric1, maskin, masking, xmaskin
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN396697
Quantity 0.1 mg
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen TACC3 (NP_006333, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6C4
Isotype IgG3 kappa
Specificity TACC3 (NP_006333, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TACC3
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 90360 DA
Gene ID 12406
UniProt NP_006333
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml

Background: The function of this gene has not yet been determined, however, it is speculated that it may be involved in cell growth and differentiation. Expression of this gene is up-regulated in some cancer cell lines, and in embryonic day 15 in mice.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Jeng, Lin, Lin et al.: "Cdh1 controls the stability of TACC3." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 21, pp. 3529-36, 2009 (PubMed).

Couch, Wang, Bamlet et al.: "Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 251-7, 2010 (PubMed).

Kiemeney, Sulem, Besenbacher et al.: "A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer." in: Nature genetics, Vol. 42, Issue 5, pp. 415-9, 2010 (PubMed).

Olson, Wang, Pankratz et al.: "Centrosome-related genes, genetic variation, and risk of breast cancer." in: Breast cancer research and treatment, Vol. 125, Issue 1, pp. 221-8, 2010 (PubMed).

Lin, Hu, Shih: "Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability." in: The Journal of cell biology, Vol. 189, Issue 7, pp. 1097-105, 2010 (PubMed).

Alternatives for antigen "Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3)", type "Antibodies"
Hosts (21), (20), (1)
Reactivities (40), (13), (3), (2)
Applications (37), (24), (19), (15), (13), (10), (4), (2)
Epitopes (5), (2), (1), (1), (1), (1), (1)