B-Cell CLL/lymphoma 7B (BCL7B) (AA 124-203) antibody

Details for Product No. ABIN396713
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Antigen
Synonyms bcl7b, zgc:103501, wu:fb94h01, zgc:85678
Epitope
AA 124-203
(9), (7), (3), (2), (2)
Reactivity
Human
(31), (18), (15), (12), (12), (12), (12)
Host
Mouse
(27), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(22), (13), (12), (10), (4), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN396713
450.00 $
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Immunogen BCL7B (NP_001698, 124 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6D2
Isotype IgG1 kappa
Specificity BCL7B (NP_001698, 124 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name BCL7B
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22195 DA
Gene ID 12406
NCBI Accession NP_001698
Research Area Cancer, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene contains a region that is highly similar to the N-terminal segment of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. The function of this gene has not yet been determined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-B-Cell CLL/lymphoma 7B (BCL7B) (AA 124-203) antibody Western Blot analysis of BCL7B expression in transfected 293T cell line by BCL7B monoclonal antibody (M01), clone 6D2. Lane 1: BCL7B transfected lysate(22 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged BCL7B is approximately 0.1 ng/mL as a capture antibody.
anti-B-Cell CLL/lymphoma 7B (BCL7B) (AA 124-203) antibody (2) anti-B-Cell CLL/lymphoma 7B (BCL7B) (AA 124-203) antibody (Image 2)
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Willer, Sanna, Jackson et al.: "Newly identified loci that influence lipid concentrations and risk of coronary artery disease." in: Nature genetics, Vol. 40, Issue 2, pp. 161-9, 2008 (PubMed).

Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Fontaine-Bisson, Renström, Rolandsson et al.: "Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population." in: Diabetologia, Vol. 53, Issue 10, pp. 2155-62, 2010 (PubMed).

Validation Images
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