C1D Nuclear Receptor Corepressor (C1D) (AA 1-142) antibody

Details for Product No. ABIN396763
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Antigen
Synonyms 1110036E10Rik, AI875855, SUN-CoR, zgc:103509, LRP1, SUNCOR, hC1D, C1d
Epitope
AA 1-142
(4), (2), (2), (1), (1), (1)
Reactivity
Human
(26), (4), (4), (2), (2), (1), (1), (1)
Host
Mouse
(16), (6), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2)
Application
Immunofluorescence (IF), Western Blotting (WB)
(24), (18), (10), (4), (1), (1)
Pubmed 5 references available
Quantity 0.05 mg
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Catalog No. ABIN396763
450.00 $
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Immunogen C1D (AAH05235, 1 a.a. ~ 142 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6H2
Isotype IgG2a kappa
Specificity C1D (AAH05235, 1 a.a. ~ 142 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name C1D
Background The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.
Synonyms: MGC12261, MGC14659, SUNCOR nuclear DNA-binding protein
Molecular Weight 16019 DA
Gene ID 10438
Research Area Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.

Restrictions For Research Use only
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-C1D Nuclear Receptor Corepressor (C1D) (AA 1-142) antibody Immunofluorescence of monoclonal antibody to C1D on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of C1D expression in transfected 293T cell line by C1D monoclonal antibody (M03), clone 6H2. Lane 1: C1D transfected lysate(16 KDa). Lane 2: Non-transfected lysate.
anti-C1D Nuclear Receptor Corepressor (C1D) (AA 1-142) antibody (2) anti-C1D Nuclear Receptor Corepressor (C1D) (AA 1-142) antibody (Image 2)
Background publications Schilders, van Dijk, Pruijn: "C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing." in: Nucleic acids research, Vol. 35, Issue 8, pp. 2564-72, 2007 (PubMed).

Schilders, Egberts, Raijmakers et al.: "C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome." in: Arthritis and rheumatism, Vol. 56, Issue 7, pp. 2449-54, 2007 (PubMed).

Rajaraman, Brenner, Butler et al.: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, 2009 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

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