|+1 404 474 4654|
|+1 888 205 9894 (TF)|
C1D Nuclear Receptor Corepressor (C1D) antibody
|Synonyms||MGC131377, LRP1, SUNCOR, SUN-CoR, MGC12261, MGC14659, AI875855, 1110036E10Rik, C1D, MGC133553|
Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||C1D (AAH05235, 1 a.a. ~ 142 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: MGC12261, MGC14659, SUNCOR nuclear DNA-binding protein|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||C1D (AAH05235, 1 a.a. ~ 142 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||16019 DA|
Background: The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Structure|
|Restrictions||For Research Use only|
Schilders, van Dijk, Pruijn: "C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing." in: Nucleic acids research, Vol. 35, Issue 8, pp. 2564-72, 2007 (PubMed).
Schilders, Egberts, Raijmakers et al.: "C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome." in: Arthritis and rheumatism, Vol. 56, Issue 7, pp. 2449-54, 2007 (PubMed).
Rajaraman, Brenner, Butler et al.: "Common variation in genes related to innate immunity and risk of adult glioma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 5, pp. 1651-8, 2009 (PubMed).
Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).
Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).
|Hosts||Rabbit (14), Goat (4), Mouse (1)|
|Reactivities||Human (18), Mouse (Murine) (5), Rat (Rattus) (5), Cow (Bovine) (3), Dog (Canine) (3), Chicken (2), Cat (Feline) (1), Xenopus laevis (1), Zebrafish (1)|
|Applications||Western Blotting (WB) (15), ELISA (13), Immunohistochemistry (IHC) (8), Immunofluorescence (IF) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)|
|Conjugates||Biotin (1), FITC (1), HRP (1)|
|Epitopes||C-Term (1), Internal Region (1), N-Term (1)|