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Arginine Vasopressin Receptor 1A (AVPR1A) antibody

Details for Product No. ABIN396775
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Antigen
Synonyms AVPR V1a, AVPR1, V1aR, AVPR, V1a, Avpr1, VT4
Reactivity
Human
(43), (26), (23), (1)
Host
Mouse
(38), (8), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(32), (23), (15), (14), (5), (1)
Pubmed 5 references available
Quantity 0.05 mg
Options
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN396775
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen AVPR1A (NP_000697, 1 a.a. ~ 53 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 7B8
Isotype IgG2a kappa
Specificity AVPR1A (NP_000697, 1 a.a. ~ 53 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name AVPR1A
Background The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.
Synonyms: AVPR1 arginine vasopressin receptor 1A
Molecular Weight 46800 DA
Gene ID 552
UniProt NP_000697
Research Area Cell Cycle, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Restrictions For Research Use only
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Arginine Vasopressin Receptor 1A (AVPR1A) antibody Western Blot analysis of AVPR1A expression in transfected 293T cell line by AVPR1A monoclonal antibody (M07), clone 7B8. Lane 1: AVPR1A transfected lysate(46.8 KDa). Lane 2: Non-transfected lysate.
Background publications Binder, Owens, Liu et al.: "Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response." in: Archives of general psychiatry, Vol. 67, Issue 4, pp. 369-79, 2010 (PubMed).

Yang, Cho, Yoo et al.: "Family-based association study of microsatellites in the 5' flanking region of AVPR1A with autism spectrum disorder in the Korean population." in: Psychiatry research, Vol. 178, Issue 1, pp. 199-201, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Yang, Cho, Yoo et al.: "Association study between single nucleotide polymorphisms in promoter region of AVPR1A and Korean autism spectrum disorders." in: Neuroscience letters, Vol. 479, Issue 3, pp. 197-200, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN396775
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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