Interleukin 1 Family Member 9 (IL1F9) (AA 1-111) antibody

Details for Product No. ABIN396796
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Antigen
Synonyms Fil1, IL-1H1, IL1RP2, Il1f9, Il36a, Il36g, IL-1F9, IL-1RP2, IL1E, IL1F9, IL1H1, RGD1563019
Epitope
AA 1-111
(3), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(18), (2)
Host
Mouse
(13), (6), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2)
Application
ELISA, Western Blotting (WB)
(20), (13), (7), (4), (4), (4), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN396796
450.00 $
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Immunogen IL1F9 (NP_062564, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 8A11
Isotype IgG1 kappa
Specificity IL1F9 (NP_062564, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL1F9
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 18721 DA
Gene ID 12406
NCBI Accession NP_062564
Research Area Cancer, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Interleukin 1 Family Member 9 (IL1F9) (AA 1-111) antibody Detection limit for recombinant GST tagged IL1F9 is approximately 0.03 ng/mL as a capture antibody.
Background publications Vos, van Sterkenburg, Rabe et al.: "Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense." in: Physiological genomics, Vol. 21, Issue 3, pp. 324-36, 2005 (PubMed).

Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Kim, Kim, Lee et al.: "Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea." in: The Journal of rheumatology, Vol. 35, Issue 8, pp. 1603-8, 2008 (PubMed).

Jung, Kang, Kim et al.: "The interleukin-1 family gene polymorphisms in Korean patients with rheumatoid arthritis." in: Scandinavian journal of rheumatology, Vol. 39, Issue 3, pp. 190-6, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

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