Interleukin 1 Family Member 9 (IL1F9) antibody

Antigen: Interleukin 1 Family Member 9 (IL1F9)

Synonyms: IL1E, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2

Clonality: Monoclonal (8A11)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN396796

Additional Information

Alternative name: IL1F9

Gene ID: 56300

UniProt: NP_062564

Immunogen: IL1F9 (NP_062564, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 8A11

Description: Other names: IL1F9, IL1H1, IL1RP2, IL1E, IL1H1, IL1RP2 interleukin 1 family, member 9

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: IL1F9 (NP_062564, 1 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 18721 DA

Comments:

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cancer, Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged IL1F9 is approximately 0.03ng/ml as a capture antibody.

Publications

Product: Vos, van Sterkenburg, Rabe et al.: "Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense." in: Physiological genomics, Vol. 21, Issue 3, pp. 324-36, 2005 (PubMed).

Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Kim, Kim, Lee et al.: "Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea." in: The Journal of rheumatology, Vol. 35, Issue 8, pp. 1603-8, 2008 (PubMed).

Jung, Kang, Kim et al.: "The interleukin-1 family gene polymorphisms in Korean patients with rheumatoid arthritis." in: Scandinavian journal of rheumatology, Vol. 39, Issue 3, pp. 190-6, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).