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Antibody
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anti-Advanced Glycosylation End Product-Specific Receptor AGER
Advanced Glycosylation End Product-Specific Receptor (AGER) antibody
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| Synonyms |
RAGE, MGC22357, AGER, MGC140817 |
| Clonality |
Polyclonal |
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Host
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Application
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| Catalog no. |
ABIN398635 |
| Quantity |
200ug (0.5 mg/ml in PBS, pH 7.4, containin...) (Variants) |
| Price |
350.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 10 Business Days |
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Alternative name
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RAGE
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Format
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Affinity-purified
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Isotype
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IgG (Matching secondary antibodies)
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Description
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The Receptor for Advanced Glycation Endproducts (RAGE) is a member of the immunoglobin superfamily of cell surface markers. This protein mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. RAGE (SwissProt Q15109) can act as receptor for amyloid beta peptide.Antibodies-Online Rabbit Anti-RAGE Polyclonal Antibody is developed in rabbit using a a KLH-coupled synthetic peptide of human RAGE.
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Specificity
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Antibodies-Online Rabbit Anti-RAGE Polyclonal Antibody can detect endogenous level of human RAGE. It has not yet been tested with other species.
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Application Notes
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.ELISA: 0.03-1 ug/mlWestern blot: 1.0 ug/mlOther applications: user-optimized
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Concentration
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0.5 mg/ml in PBS, pH 7.4, containing 30% glycerol and 0.02% sodium azide
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Purification
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Immunoaffinity chromatography
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Storage
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Rabbit Anti-RAGE Polyclonal Antibody remains stable for two to three weeks if stored at 2-8°C. Aliquot and store at -20°C or below for longer periods. Avoid repeated freeze and thaw cycles.
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Research Area
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Neurology, Alzheimer's Disease
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Restrictions
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For Research Use only
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Alternatives for antigen "Advanced Glycosylation End Product-Specific Receptor (AGER)", type "Antibodies"
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Hosts
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Rabbit (15), Goat (8), Mouse (3), Rat (1)
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Reactivities
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Human (12), Mouse (Murine) (4), Rat (Rattus) (3)
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Applications
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Western Blotting (WB) (23), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunohistochemistry (IHC) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Enzyme Immunoassay (EIA) (3), Immunocytochemistry (ICC) (2), ELISA (Detection) (1), Flow Cytometry (FACS) (1)
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Epitopes
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N-Term (2), C-Term (1)
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Alternatives 
