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Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) antibody
| Antigen | Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1) |
| Synonyms | ECGP, GP96, TRA1, GRP94, TA-3, Tra1, gp96, ERp99, Targ2, Tra-1, endoplasmin, Grp94, tra1, tra-1, fb61d09, wu:fb61d09, wu:fq25g01, Gp96, ppk98, ecgp, grp94, HSP90B1 |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB)
|
| Catalog no. | ABIN399014 |
| Quantity | 200ug (0.5 mg/ml, lyophilized with PBS, pH...) (Variants) |
| Price | 350.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Alternative name | GRP94 |
| Format | Affinity-purified |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Glucose regulated protein 94 (GRP94) is a resident protein of the endoplasmic reticulum (ER) with highly conserved sequence Lys-Asp-Glu-Leu (KDEL) at its C terminus. The KDEL sequence appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. GRP94 can serve as molecular chaperone that functions in the processing and transport of secreted proteins. It might be associated transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins. |
| Specificity | Antibodies-Online Rabbit Anti-GRP94 Polyclonal Antibody detects endogenous levels of human GRP94. Predicted to react with mouse and rat GRP94 according to sequence homology. |
Application Details
| Application Notes | Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.Western blot: 2-4 ug/mlOther Applications: useroptimized |
| Concentration | 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Purification | Immunoaffinity chromatography. |
| Storage | Rabbit Anti-GRP94 Polyclonal Antibody should be stored lyophilized until use. It remains stable in lyophilized form for at least two years if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C or below. Avoid repeated freezing and thawing cycles. |
| Research Area | Cancer, Organelles |
| Restrictions | For Research Use only |
Images
Alternatives
Alternatives for antigen "Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1)", type "Antibodies"
| Hosts | Rabbit (17), Goat (7), Rat (6), Mouse (5) |
| Reactivities | Human (30), Mouse (Murine) (15), Rat (Rattus) (10), Dog (Canine) (9), Cow (Bovine) (8), Monkey (8), Pig (Porcine) (8), Chicken (6), Sheep (Ovine) (6), Hamster (5), Horse (Equine) (5), Rabbit (5), Xenopus laevis (5), Guinea Pig (3), Fruit Fly (Drosophila melanogaster) (1) |
| Applications | Western Blotting (WB) (34), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Enzyme Immunoassay (EIA) (10), Immunofluorescence (IF) (9), Immunoprecipitation (IP) (8), ELISA (5), Flow Cytometry (FACS) (4), Immunohistochemistry (IHC) (2), ELISA (Detection) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Epitopes | C-Term (4), AA 676-803 (2) |
