Cytochrome C, Somatic (CYCS) (AA 1-80) antibody

Antigen: Cytochrome C, Somatic (CYCS)

Synonyms: cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrome c, ms(2)04445, pDMc02, DmelCG13263, CG13263, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, cyt c-p, cyt-c-p, l(2)SH1590, pDMc01, DmelCG17903, CG17903

Epitope: AA 1-80

Clonality: Monoclonal (7H8-2C12)

Host: Mouse

Reactivity: Fruit Fly (Drosophila melanogaster)

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN400732

Additional Information

Characteristics: Synonyms: CYCS, CYC

Alternative name: Cytochrome c

Swiss-Prot: P99999

Immunogen: Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of Pigeon CYT. Remarks: Antigen Modification: aa 1-80

Cross-Reactivity: Fruit Fly (Drosophila melanogaster), Horse (Equine), Hamster, Human, Mouse (Murine), Rat (Rattus)

Isotype: IgG2b  (Matching secondary antibodies)

Clone: 7H8-2C12

Description: Cytochrome C is an electron transporting protein that resides within the intermembranespace of the mitochondria, where it plays a critical role in the process of oxidativephosphorylation and production of cellular ATP. An increasing amount of interest has beendirected toward the role which cytocrome C has been demonstrated to play in apoptoticprocesses. Following exposure to apoptotic stimuli, cytochrome C is rapidly released fromthe mitochondria into the cytosol, an event which may be required for the completion ofapoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase3, an ICE family molecule that is a key effector of apoptosis.

Specificity: The antibody recognizes an epitope within amino acids 93-104 of Pigeon Cytochrome C. Species Reactivity: Tested: Pigeon. Expected from sequence similarity: Drosophila, Hamster, Equine (Horse), Human, Mouseand Rat.

Synonyms: cycs, CYCS, CYC, HCS, THC4, cyc, hcs, cyct, MGC75709, MGC89066, DKFZp468F1016, MGC128356, CYCSA, MGC93634, Cyt-c1, CytC-1, CytC1, Cytc, Cytc-d, DC3, bln, bs30f07.y1, cyt c-d, cyt-c-d, cyt.c, cytochrome c, ms(2)04445, pDMc02, DmelCG13263, CG13263, Cyt-c2, CytC-2, Cytc-p, DC4, DMc01, cyt c-p, cyt-c-p, l(2)SH1590, pDMc01, DmelCG17903, CG17903

Application Details

Application Notes: Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.5 mg/ml

Purification: Purified

Buffer: PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide aspreservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only