FBXW11 antibody (N-Term)

Catalog No. ABIN401257

Product Details anti-FBXW11 Antibody

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Cow, Chicken, Horse, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts with betaTrCP2 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine, Bovine, Chimpanzee, Chicken, Horse.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding to a region near the N-terminal of human betaTrCP2 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/10,000 - 1/100,000. Western Blot: 1/200 - 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for FBXW11

Target: FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))

Alternative Name: FBW1B (FBXW11 Products)

Synonyms: BTRC2 antibody, BTRCP2 antibody, FBW1B antibody, FBXW1B antibody, Fbw11 antibody, Hos antibody, 2310065A07Rik antibody, AA536858 antibody, Fbxw1b antibody, HOS antibody, btrc2 antibody, fbxw11a antibody, wu:fa12e12 antibody, wu:fb11f03 antibody, zgc:63728 antibody, fbxw11 antibody, fbxw11b antibody, fbxw1b antibody, wu:fd14d12 antibody, wu:fi43f07 antibody, F-box and WD repeat domain containing 11 antibody, F-box and WD-40 domain protein 11 antibody, F-box/WD repeat-containing protein 11 antibody, F-box and WD repeat domain containing 11b antibody, F-box and WD repeat domain containing 11a antibody, FBXW11 antibody, Fbxw11 antibody, LOC100199403 antibody, fbxw11b antibody, fbxw11a antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.Synonyms: BTRCP2, F-box and WD repeats protein beta-TrCP2, F-box/WD repeat-containing protein 11, F-box/WD repeat-containing protein 1B, FBXW11, FBXW1B, HOS, Homologous to Slimb protein, KIAA0696, beta-TrCP2

Gene ID: 23291

NCBI Accession: NP_036432

UniProt: Q9UKB1