FBXO43 antibody (N-Term)

Catalog No. ABIN401259

Product Details anti-FBXO43 Antibody

Target: FBXO43 (F-Box Protein 43 (FBXO43))

Binding Specificity: N-Term

Reactivity: Human, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO43 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is directed against Fbp5B protein.

Cross-Reactivity (Details): Species reactivity (expected):Chimpanzee (100 %).
Species reactivity (tested):Human.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding to a region approximately 60 residues downstream of the amino terminal end of human Fbp5B protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1: 10,000 - 1: 50,000. Western blot: 1: 500 - 1: 3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.3 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or for longer (in aliquots) at -20 °C or below.

Target Details for FBXO43

Target: FBXO43 (F-Box Protein 43 (FBXO43))

Alternative Name: FBXO43 (FBXO43 Products)

Synonyms: EMI2 antibody, ERP1 antibody, FBX43 antibody, 4930533G20Rik antibody, Emi2 antibody, emi2 antibody, erp1 antibody, Xerp1 antibody, zgc:66488 antibody, F-box protein 43 antibody, F-box protein 43 L homeolog antibody, FBXO43 antibody, Fbxo43 antibody, fbxo43 antibody, fbxo43.L antibody

Background: Fbp5B (also called F-Box protein 43 or Fbx043) is a relatively new member of the F-box protein family that is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B

Gene ID: 286151

NCBI Accession: NP_001025031

UniProt: Q4G163