SMARCAL1 antibody (AA 80-96)

Catalog No. ABIN401264

Product Details anti-SMARCAL1 Antibody

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Binding Specificity: AA 80-96

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCAL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This affinity purified antibody is directed against SmarcAL1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Cross reactivity with SmarcAL1 from other sources is not expected due to significant sequence divergence within the immunogen sequence.
Species reactivity (tested):Human.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding aa 80-96 of human SmarcAL1 protein

Isotype: IgG

Application Details

Application Notes: Western blot: 1: 500 - 1: 3,000. ELISA: 1: 16,000 - 1: 64,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for SMARCAL1

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Alternative Name: SMARCAL1 / HARP (SMARCAL1 Products)

Synonyms: SMARCAL1 antibody, im:7145331 antibody, si:ch211-239d11.1 antibody, harp antibody, hharp antibody, 6030401P21Rik antibody, AI851716 antibody, Mharp antibody, HARP antibody, HHARP antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog antibody, SMARCAL1 antibody, smarcal1 antibody, Smarcal1 antibody, smarcal1.L antibody

Background: SmarcAL1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1) is also known as HARP, HepA Related Protein, HHARP, SMARCA like Protein 1 and SWI/SNF Related. SmarcAL1 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.Synonyms: HepA-related protein, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, Sucrose nonfermenting protein 2-like 1

Gene ID: 50485

NCBI Accession: NP_001120679

UniProt: Q9NZC9

Pathways: Embryonic Body Morphogenesis