RIF1 antibody (AA 2406-2419)

Catalog No. ABIN401303

Product Details anti-RIF1 Antibody

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Binding Specificity: AA 2406-2419

Reactivity: Human, Mouse, Dog, Rat, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIF1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is directed against Rif1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Canine, Chimanzee.
Species reactivity (tested):Mouse.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding amino acids 2406-2419 of Mouse Rif1

Isotype: IgG

Application Details

Application Notes: ELISA: 1/5000 - 1/40000. Western Blot: 1/500 - 1/3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.6 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for RIF1

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Alternative Name: RIF1 (RIF1 Products)

Background: Rif1 (also known as telomere-associated protein RIF1 and Rap1-interacting factor 1) is a mouse ortholog of the yeast Rif1 family of telomere-associated proteins identified on the basis of its high expression in primordial germ cells and embryo-derived pluripotent stem cell lines. Mouse Rif1 is a protein involved in negative regulation of telomere length. It is also localized to ATM dependent DNA damage foci and may act at the chromatin level to allow access to some factors.Synonyms: Rap1-interacting factor 1 homolog, Telomere-associated protein RIF1

Gene ID: 51869

NCBI Accession: NP_780447

UniProt: Q6PR54

Pathways: Stem Cell Maintenance