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Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody

Details for Product No. ABIN401309, Supplier: Log in to see
Antigen
  • HD1
  • RPD3
  • Hdac1
  • Gm1824
  • EG15181
  • Hdac1-ps
  • ENSMUSG00000061062
  • Rpd3
  • GB14706
  • hdac1
  • rpd3
  • yaf1
  • gon-10
  • hdac1-b
  • rpd3l1
  • ARABIDOPSIS HISTONE DEACETYLASE 1
  • ARABIDOPSIS HISTONE DEACETYLASE 19
  • ATHD1
  • ATHDA19
  • ATRPD3A
  • F20D10.250
  • F20D10_250
  • HDA1
  • HDA19
  • HISTONE DEACETYLASE
  • HISTONE DEACETYLASE 19
  • HISTONE DEACETYLASE19
  • RPD3A
  • histone deacetylase 1
  • CG7471
  • DHDAC1
  • DRpd3
  • DmHDAC1
  • Dmel\\CG7471
  • E(var)3-64BC
  • HDAC
  • HDAC-1
  • HDAC1
  • Rpd3/HDAC
  • Su(var)3-26
  • Su(var)326
  • Su(var)328
  • dHDAC-1
  • dHDAC1
  • dRPD3
  • dRpd3
  • dmHDA401
  • drpd3
  • l(3)04556
  • l(3)64Cc
  • rpd[3]
  • GON-10
  • RPD3L1
  • MommeD5
  • chunp6919
  • hdac-1
  • mp:zf637-2-001987
  • wu:fb19h11
  • wu:fi06f03
  • zgc:101582
  • zgc:65818
  • hdac1b
Alternatives
anti-Human Histone Deacetylase 1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 466-482
88
32
26
22
18
18
18
15
10
10
10
10
9
8
8
8
8
5
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Chimpanzee, Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
359
138
121
10
9
5
5
4
4
3
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
280
76
18
Clonality
Polyclonal
Conjugate
Un-conjugated
10
10
10
10
10
10
3
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
323
189
102
99
61
41
21
16
11
10
6
4
4
3
1
1
1
1
1
Supplier
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Immunogen Synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1
Isotype IgG
Specificity This antibody is directed against HDAC-1 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Chimpanzee, Bovine, Chicken.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name HDAC1 (HDAC1 Antibody Abstract)
Background HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.Synonyms: HD1, Histone deacetylase 1, RPD3L1
Gene ID 3065
NCBI Accession NP_004955
UniProt Q13547
Research Area Cardiovascular, Hypertrophy, Wnt, DNA/RNA, Transcription Factors, Wnt Signaling
Pathways Neurotrophin Signaling Pathway
Application Notes Western Blot: 1/1,000 - 1/5,000. ELISA: 1/10,000 - 1/50,000. Immunohistochemistry: 1/200 - 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.33 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Supplier Images
 image for anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody (ABIN401309) anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody
 image for anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody (ABIN401309) anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody (Image 2)
 image for anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody (ABIN401309) anti-Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody (Image 3)
Background publications Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, 2004 (PubMed).