SLIT3 antibody (AA 1164-1177)

Catalog No. ABIN401312

Product Details anti-SLIT3 Antibody

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Binding Specificity: AA 1164-1177

Reactivity: Mouse, Human, Rat, Cow, Dog, Chicken, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIT3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is directed against SLIT-3 protein.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine, Bovine, Mouse, Chimpanzee, Chicken.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 1164-1177 of Human SLIT-3 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.83 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for SLIT3

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Alternative Name: SLIT3 (SLIT3 Products)

Synonyms: MGC146100 antibody, zgc:111911 antibody, MEGF5 antibody, SLIL2 antibody, SLIT1 antibody, Slit-3 antibody, slit2 antibody, Slil2 antibody, Slit1 antibody, Megf5 antibody, slit guidance ligand 3 antibody, slit homolog 3 (Drosophila) antibody, Slit3 antibody, slit3 antibody, SLIT3 antibody, LOC100125612 antibody, Slit3 antibody

Background: SLIT-3 (also known as multiple epidermal growth factorlike domain 5 and Slit homolog 3 protein) is a Slit protein. The 'slit' gene has been shown to play a critical role in central nervous system midline formation. In addition to SLIT3 there are two additional human 'slit' homologs, which are termed SLIT1 and SLIT2. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. SLIT proteins may also participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Slit-3 is a secreted protein predominantly expressed in thyroid. Multiple isoforms have been reported for this product.Synonyms: KIAA0814, MEGF5, Multiple epidermal growth factor-like domains protein 5, SLIL2, SLIT-3, Slit homolog 3 protein

Gene ID: 6586

NCBI Accession: NP_003053

UniProt: O75094

Pathways: Regulation of Cell Size