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ABCB5 antibody (Internal Region)

ABCB5 Reactivity: Human, Monkey WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN401433
  • Target See all ABCB5 Antibodies
    ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))
    Binding Specificity
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 29
    • 4
    • 1
    Human, Monkey
    Host
    • 22
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 25
    • 5
    Polyclonal
    Conjugate
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB5 antibody is un-conjugated
    Application
    • 17
    • 14
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific for ABCB5 protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Monkey (85 %), Rat (68 %), Mouse (62 %).
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography
    Immunogen
    Synthetic peptide corresponding to residues corresponding to an internal region of Human ABCB5
    Isotype
    IgG
    Top Product
    Discover our top product ABCB5 Primary Antibody
  • Application Notes
    ELISA: 1/10,000-1/50,000. Western Blot: 1/20,000. Trial Size: ELISA: 1/10,000- 1/15,000. Western Blot: 1/10,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))
    Alternative Name
    ABCB5 (ABCB5 Products)
    Synonyms
    ABCB5alpha antibody, ABCB5beta antibody, EST422562 antibody, 9230106F14Rik antibody, RGD1566342 antibody, ABCB5 antibody, mdr1 antibody, im:7158730 antibody, wu:fc18f02 antibody, wu:fi81f06 antibody, ATP binding cassette subfamily B member 5 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antibody, ATP-binding cassette sub-family B member 5 antibody, ABCB5 antibody, Abcb5 antibody, abcb5 antibody, TGME49_249820 antibody, PAAG_04387 antibody, VDBG_00160 antibody, VDBG_02292 antibody
    Background
    ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.Synonyms: ATP-binding cassette sub-family B member 5
    Gene ID
    340273
    NCBI Accession
    NP_001157413
    UniProt
    Q2M3G0
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