SYT2 antibody (pThr202)

Catalog No. ABIN401604

Product Details anti-SYT2 Antibody

Target: SYT2 (Synaptotagmin II (SYT2))

Binding Specificity: pThr202

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT2 antibody is un-conjugated

Application: Immunofluorescence (IF)

Specificity: Synaptotagmin II (Phospho-Thr202) Antibody detects endogenous levels of Synaptotagmin II only when phosphorylated at threonine202.

Purification: Affinity chromatography

Immunogen: Synthesized phosphopeptide derived from human Synaptotagmin II around the phosphorylation site of threonine 202 (R-K-TP-L-N)

Application Details

Application Notes: Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for SYT2

Target: SYT2 (Synaptotagmin II (SYT2))

Alternative Name: Synaptotagmin-2 (SYT2 Products)

Synonyms: SytII antibody, RATSYNII antibody, SYNII antibody, R74640 antibody, mKIAA4194 antibody, si:ch211-236j4.1 antibody, synaptotagmin 2 antibody, synaptotagmin II antibody, synaptotagmin IIa antibody, SYT2 antibody, Syt2 antibody, syt2a antibody, syt2 antibody

Background: SYT2 (Synaptotagmin II) belongs to the synaptotagmin family of multi-domained, integral membrane proteins of synaptic vesicles which are thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.Synonyms: SYT-2, SYT2, SYTII, Synaptotagmin 2, Synaptotagmin II

Gene ID: 127833

NCBI Accession: NP_001129976

UniProt: Q8N9I0

Pathways: Synaptic Vesicle Exocytosis