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CPI-17 antibody (Isoform alpha, Thr38)
PPP1R14A
Reactivity: Human, Mouse, Rat
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CPI-17 Antibody
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Target
See all CPI-17 (PPP1R14A) Antibodies
CPI-17 (PPP1R14A)
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
Binding Specificity
All epitopes for CPI-17 antibodies
Isoform alpha, Thr38
Reactivity
All reactivities for CPI-17 antibodies
Human, Mouse, Rat
Host
All hosts for CPI-17 antibodies
Rabbit
Clonality
All clonalities for CPI-17 antibodies
Polyclonal
Conjugate
All conjugates for CPI-17 antibodies
This CPI-17 antibody is un-conjugated
Application
All applications for CPI-17 antibodies
Immunofluorescence (IF)
Specificity
CPI17α antibody detects endogenous levels of total CPI17α protein.
Purification
Affinity chromatography
Immunogen
Synthesized non-phosphopeptide derived from human CPI17alpha around the phosphorylation site of threonine 38 (R-V-TP-V-K)
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Discover our top product PPP1R14A Primary Antibody
Alternatives
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Application Details
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Application Notes
Immunofluorescence: 1/100 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target Details for CPI-17
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Target
CPI-17 (PPP1R14A)
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
Alternative Name
PPP1R14A (PPP1R14A Products )
Synonyms
MGC81874 antibody, cpi-17 antibody, ppp1inl antibody, CPI-17 antibody, im:7147597 antibody, ppp1r14a antibody, zgc:110700 antibody, PPP1R14A antibody, CPI17 antibody, PPP1INL antibody, Cpi17 antibody, 1110001M11Rik antibody, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antibody, protein phosphatase 1 regulatory inhibitor subunit 14A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14A antibody, ppp1r14a.L antibody, ppp1r14a antibody, ppp1r14aa antibody, PPP1R14A antibody, Ppp1r14a antibody
Background
PKC potentiated inhibitor protein-17 is a 17 kDa protein. Expressed in smooth muscles and neuronal cells, CP117 is a myosin phosphatase inhibitor protein. Phosphorylation of CP117 at Thr38 enhances its inhibitory effect by 100 fold. Once phosphorylated, CP117 inhibits PP1c and MLCP holoenzyme activity.Synonyms: 17 kDa PKC-potentiated inhibitory protein of PP1, CPI-17, CPI17, PPP1INL, Protein phosphatase 1 regulatory subunit 14A
Gene ID
94274
NCBI Accession
NP_150281
UniProt
Q96A00
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