Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

P2RX7 antibody (N-Term)

P2RX7 Reactivity: Human, Mouse, Rat, Dog WB, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN401660
  • Target See all P2RX7 Antibodies
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Binding Specificity
    • 15
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 58
    • 40
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 57
    • 2
    • 2
    • 1
    Goat
    Clonality
    • 58
    • 4
    Polyclonal
    Conjugate
    • 28
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P2RX7 antibody is un-conjugated
    Application
    • 48
    • 26
    • 23
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Sequence
    YETNKVTRIQ SMNY-C
    Specificity
    This antibody recognizes P2X7 receptor.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography
    Immunogen
    Peptide with sequence from the N-Terminus of the protein sequence (NP_002553.2). Genename: P2RX7
    Top Product
    Discover our top product P2RX7 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/16000. Western blot: 1 - 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Graziano, Desdouits, Garzetti, Podini, Alfano, Rubartelli, Furlan, Benaroch, Poli: "Extracellular ATP induces the rapid release of HIV-1 from virus containing compartments of human macrophages." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 25, pp. E3265-73, (2015) (PubMed).

  • Target
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Alternative Name
    P2RX7 / P2X7 (P2RX7 Products)
    Synonyms
    p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
    Background
    The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.Synonyms: ATP receptor, P2X purinoceptor 7, P2Z receptor, Purinergic receptor
    Molecular Weight
    68.6kDa (NP_002553.2).
    Gene ID
    5027
    NCBI Accession
    NP_002553
    UniProt
    Q99572
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
You are here:
Support