Perilipin 5 (PLIN5) (AA 451-463), (C-Term) antibody

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Synonyms LSDA5, LSDP5, MLDP, OXPAT, 2310076L09Rik, AI415325, AW109675, Lsdp5, PAT-1
C-Term, AA 451-463
(8), (6), (5), (2)
Cow (Bovine), Human, Mouse (Murine)
(15), (13), (6)
Guinea Pig
(14), (2)
(2), (2), (2), (2), (2)
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(16), (7), (2)
Pubmed 3 references available
Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide corresponding to the C-terminal (aa 451-463) of Human MLDP
Specificity This antibody reacts with MLDP = myocardial lipid droplet protein (also described as OXPAT/PAT-1), MW 50,844 (calculated from aa sequence data), Apparent Mr 52,000 (after SDS-PAGE). MLDP pertains to the PAT-family proteins, covering the surface of cytoplasmic lipid droplets and sharing a homologuous domain called PAT. Additional PAT proteins include adipophilin (ADRP), perilipin, and TIP47 which are expressed in differentiation-related stages of lipid metabolism. Tissue Immunolocalization: MLDP is positively detected in heart, skeletal muscle. Tested Reactivities on Cultured Cell Lines: HaCat (human), SV80 (human), 3T3-L1 (mouse).
Cross-Reactivity (Details) Species reactivity (tested):Human, Bovine, Mouse, Rat.
Purification Serum
Alternative Name Perilipin-5 (PLIN5 Antibody Abstract)
Background Synonyms: LSDP5, Lipid storage droplet protein 5, OXPAT, PLIN5
Gene ID 440503
NCBI Accession NP_001013728
UniProt Q00G26
Application Notes Western Blot: 1/2000. Immunohistochemistry on frozen sections: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Wolins, Quaynor, Skinner et al.: "OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization." in: Diabetes, Vol. 55, Issue 12, pp. 3418-28, 2006 (PubMed).

Wolins, Brasaemle, Bickel: "A proposed model of fat packaging by exchangeable lipid droplet proteins." in: FEBS letters, Vol. 580, Issue 23, pp. 5484-91, 2006 (PubMed).

Garcia-Carbonero, Supko, Maki et al.: "Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 23, Issue 24, pp. 5484-92, 2005 (PubMed).

Catalog No. ABIN401672
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