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Perilipin 5 (PLIN5) (C-Term), (AA 451-463) antibody

Details for Product No. ABIN401672
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Antigen
Synonyms LSDA5, LSDP5, MLDP, OXPAT, 2310076L09Rik, AI415325, AW109675, Lsdp5, PAT-1
Epitope
C-Term, AA 451-463
(7), (7), (6), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine)
(16), (14), (7)
Host
Guinea Pig
(16), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(18), (8), (1)
Pubmed 3 references available
Quantity 0.1 mL
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Catalog No. ABIN401672
511.50 $
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Immunogen Synthetic peptide corresponding to the C-terminal (aa 451-463) of Human MLDP
Sequence CPVKHTLMPELDF
Specificity MLDP = myocardial lipid droplet protein (also described as OXPAT/PAT-1), MW 50,844 (calculated from aa sequence data), Apparent Mr 52,000 (after SDS-PAGE). MLDP pertains to the PAT-family proteins, covering the surface of cytoplasmic lipid droplets and sharing a homologuous domain called PAT. Additional PAT proteins include adipophilin (ADRP), perilipin, and TIP47 which are expressed in differentiation-related stages of lipid metabolism. Tissue Immunolocalization: MLDP is positively detected in heart, skeletal muscle. Tested Reactivities on Cultured Cell Lines: HaCat (human), SV80 (human), 3T3-L1 (mouse).
Purification Serum
Alternative Name Perilipin-5
Background Alternate names: LSDP5, Lipid storage droplet protein 5, OXPAT, PLIN5
Gene ID 440503
NCBI Accession NP_001013728
UniProt Q00G26
Application Notes Western Blot: 1/2000. Immunohistochemistry on frozen sections: 1/100 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Garcia-Carbonero, Supko, Maki et al.: "Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 23, Issue 24, pp. 5484-92, 2005 (PubMed).

Wolins, Brasaemle, Bickel: "A proposed model of fat packaging by exchangeable lipid droplet proteins." in: FEBS letters, Vol. 580, Issue 23, pp. 5484-91, 2006 (PubMed).

Wolins, Quaynor, Skinner et al.: "OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization." in: Diabetes, Vol. 55, Issue 12, pp. 3418-28, 2006 (PubMed).

Validation Images
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