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Neuronal PAS Domain Protein 1 (NPAS1) (Middle Region) antibody

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Antigen
Synonyms si:dkeyp-13e2.1, MOP5, PASD5, bHLHe11
Epitope
Middle Region
(8), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(24), (13), (10)
Host
Rabbit
(26)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1)
Application
Western Blotting (WB)
(23), (10), (7), (2), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human NPAS1
Blocking Peptide Blocking peptide for this product available: ABIN980827
Sequence SSSSSSSLAD TPEIEASLTK VPPSSLVQER SFFVRMKSTL TKRGLHVKAS
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against NPAS1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name NPAS1 (NPAS1 Antibody Abstract)
Background NPAS1 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development.
Molecular Weight 63 kDa
Gene ID 4861
NCBI Accession NM_002517, NP_002508
UniProt Q99742
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 590 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Neuronal PAS Domain Protein 1 (NPAS1) (Middle Region) antibody (ABIN404821) WB Suggested Anti-NPAS1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Hogenesch, Chan, Jackiw et al.: "Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8581-93, 1997 (PubMed).

Catalog No. ABIN404821
$289.00
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